Synthesis of a New DPTYEAP Ligand and Its Complexes with Their Assessments on Physical Properties, Antioxidant, and Biological Potential to Treat Breast Cancer

A new series of complexes the 2-((1E,2E)-1,2-diphenyl-2-(thiazol-2-ylimino)ethylidene)amino)phenol (DPTYEAP) has been synthesized by reaction ligand with metal chlorides Ni(II), Cu(II), Pt(IV), and AgNO3 in ethanol as a solvent. The was prepared for two steps. In first step, compound (A) reacting 2-aminothiazol benzil ethanol. Another step is preparation from 2-aminophenol. structures its were confirmed FTIR, 1H-13C-NMR, UV-Vis spectra, melting points, molar conductivity (C, H, N), magnetic susceptibility. 1:2 ratio Pt(IV) 1:1 (M:L) Ag(I) complexes. geometric shape all octahedral, except complex, which tetrahedral. antioxidant test compounds carried out. anticancer conducted each ligands platinum(IV) it found that platinum complex more effective against breast cancer cells (MCF-7); thus, can be used potential drug after studying well.